Nigerian Food and Prostate Cancer Prevention.

Posted on July 2, 2015 by Dr. Gary Pack

Dietary polyphenols can be both antioxidant and chemopreventive. This article reviews the following Nigerian foods: Dacryodes edulis fruit (bush butter tree), Moringa oleifera, and Syzygium aromaticum (cloves). These contain polyphenols which are active in the prostate: Ellagic acid, gallate, methylgallate, catechol, kaempferol, and quercetin. Canarium schweinfurthi Engl (African elemi) oil contains 10 poyphenols. The following […]

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Chemoprevention of Prostate Cancer Stem Cells with PSP.

Posted on April 28, 2015 by Dr. Gary Pack

Prostate cancer is the most common male cancer in the western world. When surgery is not possible, *hormone ablation therapy is used; however, most patients eventually relapse. Chemotherapy has poor results with excessive side effects. Prostate cancer stem cells (CSCs) have been identified as the possible source of prostate cancer, but these cells are highly […]

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Conditions: Cancer, Prostate cancer, Prostatic intraepithelial neoplasia

Supplements: Medicinal mushrooms, PSP, Tocotrienols, Turkey tail mushroom (Coriolus versicolor), Vitamin E

Foods: Mushrooms

Miscellaneous: Chemoprevention, Hormone ablation therapy, Prostaspheres, Prostate cancer stem cells, Stem cells (progenitor), Testicles (testes), Testosterone

COX Inhibitors in Ovarian Cancer.

Posted on April 27, 2015 by Dr. Gary Pack

COX-1 (cyclooxygenase-1) and COX-2 (cyclooxygenase-2) enzymes control the onset and progression of a number of cancers. COX-1 and COX-2 inhibitors are well known anti-inflammatory enzymes found in plants. Pharmaceutical versions of these two inhibitors are available. NSAIDs (nonsteroidal anti-inflammatory drugs), such as aspirin, are believed to inhibit cancer by inhibition of COX activity, and long-term […]

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Conditions: Apoptosis, Cancer, Inflammation, Ovarian cancer

Miscellaneous: Aspirin, Celecoxib, Chemoprevention, COX-1, COX-2, COX-2 inhibitor, Ibuprofen, Proliferation, Synergistic

Calcium as a Preventive for Colorectal Cancer.

Posted on November 26, 2013 by Dr. Gary Pack

Calcium shows promise for chemoprevention of colorectal cancer (CRC). The way that calcium prevents CRC is unknown, but this study was done to research more information. Mice were studied with CRC induced chemically by DMH (1.2-dimethylhydrazine) injections. The mice were divided into groups with one group receiving normal mice feed and another receiving a high […]

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Conditions: Adhesion, Cancer, Colorectal adenoma, Colorectal cancer, Differentiation

Supplements: Calcium, Calcium carbonate

Miscellaneous: Arachidonic acid, Chemoprevention, Genetics, Proliferation

Selenium and Apoptosis.

Posted on September 24, 2013 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Apoptosis. Autophagy. Cancer prevention. Cancer therapy. Caspase. Cell death. Glutathione. Reactive oxygen species. Sodium selenite. Trace element. Selenium. To order the above products call 415-863-0620 and […]

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Conditions: Apoptosis, Autophagy, Cancer

Supplements: Glutathione, Selenium, Trace elements

Miscellaneous: Chemoprevention, Element

Resveratrol and Cancer.

Posted on July 12, 2013 by Dr. Gary Pack

Resveratrol (Rsv) is a polyphenol found in grape skin, red wine, bilberries, blackberries and other foods. Resveratrol is chemopreventive of some cancers, atherosclerosis, aging and inflammatory diseases. The researchers studied the effects of Rsv on a line of heart muscle tumor cells from mice. Cancers of heart muscles are rare, but cannot be removed easily. […]

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Conditions: Aging, Apoptosis, Arteriosclerosis (atherosclerosis), Cancer, Cell death, Chemotherapy, Heart disease, Heart muscle cancer, Inflammation, Irradiation

Supplements: Resveratrol

Foods: Bilberry, Blackberry, Functional food, Grapes, Red wine

Miscellaneous: Chemoprevention, Muscle, Neurotransmitters, Norepinephrine, Nutraceuticals, Polyphenols

Scallions and Colorectal Cancer.

Posted on October 8, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Alternative treatment, Angiogenesis, Apoptosis, Cancer, colorectal, Chemoprevention, COX-2, Cytokines, Diet, Inflammatory markers, iNOS, Malignant, Proliferation, Risk reduction, Scallion (Allium fistulosum), Tumor invasion, Vegetable. PMID: 23024755. Summary […]

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Conditions: Angiogenesis, Apoptosis, Cancer, Colorectal cancer, Inflammation, Proliferation

Foods: Scallion (Allium fistulosum), Vegetables

Miscellaneous: Alternative Medicine, Chemoprevention, COX-2, Cytokines, Diet, Nitric oxide synthetase

PSP and Prostate Cancer.

Posted on August 1, 2011 by Dr. Gary Pack

A current treatment for prostate cancer is a pharmaceutical called finasteride, which is a 5-alpha reductase* inhibitor. One clinical trial showed that finasteride reduced prostate cancer incidence in 25% of patients, but did so with significant side effects. There is a need for better therapy for better prostate cancer. Prostate cancer stem cells (CSC) are […]

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Conditions: Cancer, Prostate cancer

Supplements: PSP, Turkey tail mushroom (Coriolus versicolor)

Miscellaneous: 5-alpha reductase, 5-alpha reductase inhibitor, Chemoprevention, Finasteride, Prostaspheres, Stem cells (progenitor)

Prostate Cancer Prevention.

Posted on July 27, 2011 by Dr. Gary Pack

Prostate cancer (PCa) is becoming a widespread problem worldwide as our population continues to age. Prevention is increasingly important! As well, early treatment will likely be beneficial since PCa is often slow to progress. Selenium, alpha-tocopheral, isoflavones, lycopene, green tea polyphenols, calcium and resveratrol are proposed beneficial in preventing the progress of PCa. The lowest […]

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Alpha Lipoic Acid Protects From Chromate Damage.

Posted on December 22, 2010 by Dr. Gary Pack

Chromate, or Cr(6+,) is carcinogenic, probably due to damage to the DNA. Cr(6+) causes free radical formation which is toxic to DNA and can lead to carcinogenesis. Treatment studies of Cr(6+) using N-acetyl carnitine (NAC,) EGCG from green tea, vitamin E and vitamin C show little benefit. Lipoic acid (LA or alpha lipoic acid,) an […]

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Conditions: Carcinogenesis, Chemotherapy, Chromate toxicity

Supplements: Alpha lipoic acid, EGCG (epigallocatechin gallate), Hydrogen peroxide, N-acetylcysteine (NAC), Vitamin C (ascorbic acid), Vitamin E

Miscellaneous: Antioxidant, Chelation, Chemoprevention, DNA

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