Natural Angiogenesis Inhibitors and Cancer-Part 2.

Posted on July 5, 2015 by Dr. Gary Pack

Adipocytokines are polypeptides produced by fat cells.They are associated with obesity, hyperinsulinemia, chronic vascular disease and cancer.The adipocytokines which promote angiogenesis (the growth of new blood vessels) include vascular endothelial growth factor (VEGF,) hepatocyte growth factor (HGF,) leptin, tumour necrosis factor alpha, heparin-binding epidermal growth factor, insulin-like growth factor and interleukin-6 (IL-6.) Whole plant extracts […]

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Conditions: Angiogenesis, Apoptosis, Bladder cancer, Breast cancer, Cancer, Chronic myelogenous leukemia, Hyperinsulinemia, Inflammation, Multidrug resistance (MDR), Obesity, Vascular disease

Supplements: Asian ginseng (Panax ginseng), Curcumin, Daidzein, Dong quai (Angelica sinensis, EGCG (epigallocatechin gallate), Eicosapentanoic acid (EPA), European mistletoe (Viscum album), Feverfew (Tanacetum parthenium), Genistein, Ginger (Zingiber officinale), Ginseng, Grape seed extract, Hibiscus (Hibiscus sabdariffa), Holy basil (Ocimum sanctum), Lapacho (Pau d'arco), Omega-6 fatty (linoleic) acid, Pau d'arco (Tabebuia avellanedae), Quercetin, Red sage (Salvia miltiorrhiza), Resveratrol, Rosemary (Rosmarinus officinalis), Skullcap (Scutellaria baicalensis), Turmeric (Curcuma longa)

Miscellaneous: Anti-angiogenesis, Anticoagulant, Arachidonic acid, COX-2, COX-2 inhibitor, Epidermal growth factor, Prostaglandins, Tyrosine kinase, VEGF (vascular endothelial growth factor)

Diabetes and Cancer Risk

Posted on May 13, 2015 by Dr. Gary Pack

Diabetes is associated, generally, with an increased risk of cancer. It is unknown whether diabetes treatment increases cancer risk. The locations of the cancers involved are liver, endometrium, pancreas, colorectum, bladder, and breast. The increased risk of cancer in diabetic patients is true in Western countries as well as in Asian countries, and is thought […]

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Conditions: Apoptosis, Bladder cancer, Breast cancer, Cancer, Carcinogenesis, Chemotherapy, Colon cancer, Colorectal cancer, Diabetes, Endometrial cancer, Epidemic, Hyperglycemia, Hyperinsulinemia, Insulin resistance, Liver cancer, Metastases, Mutation, Oxidative stress, Pancreatic cancer, Prostate cancer

Miscellaneous: Asia, Diet, Exercise, Metformin, PET scan, Weight management

Vitamin D and Women’s Reproductive Health.

Posted on May 11, 2015 by Dr. Gary Pack

In North America and Western Europe very little vitamin D comes from the diet, and fish is a good source. Most of our vitamin D comes from sun exposure. The natural form of vitamin D is 1,25(OH)2D3. Blood testing is done on 25(OH)D3, with levels below 30 ng/ml being low. Vitamin D is important for […]

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Histidine and Carnosine and Fatty Liver.

Posted on February 5, 2011 by Dr. Gary Pack

Carnosine is a dipeptide (2 amino acids) made of beta-alanine and l-histidine joined together by the enzyme, carnosine synthetase. Carnosine is found in liver, brain and skeletal muscles. This study was done to see whether carnosine or histidine can reduce lipid formation in the liver and fat tissue at times of a high fat diet […]

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Conditions: Cirrhosis, Fatty liver (hepatic steatosis), Hyperinsulinemia, Hyperlipidemia, Insulin resistance, Kidney disease, Obesity

Supplements: Alanine, Beta-alanine, Beta-alanine-L-histidine, Carnosine

Foods: Beef, Chicken, Fructose

Naringenin, Insulin and the Metabolic Syndrome.

Posted on September 19, 2009 by Dr. Gary Pack

Insulin resistance is an increasing problem, worldwide. A number of plants have the property of being “insulin sensitizers,” making the person more sensitive to insulin. Insulin resistance is a problem in which tissues become resistant to insulin with resulting poor control of glucose and lipid levels. Fructose in rodents produces a decline in insulin sensitivity, […]

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Conditions: Diabetes, Hyperglycemia, Hyperinsulinemia, Hypertension, Insulin resistance, Metabolic syndrome

Supplements: Bioflavonoids

Foods: Citrus fruit, Fenugreek, Fructose, Grapefruit

Miscellaneous: Flavonoids, Naringenin

Dietary Fiber, Weight Gain, and Cardiovascular Disease.

Posted on April 21, 2007 by Dr. Gary Pack

Cardiovascular disease (CVD) is the leading cause of death in the United States. Fiber consumption in the diet alters insulin secretion, insulin blood levels and may alter CVD risk. Fiber with a meal reduces the insulin by slowing the rate of absorption of nutrients. The present study was done to further investigate fiber intake, insulin […]

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Conditions: Aging, Cardiovascular disease, Copper deficiency, Exercise, Hyperinsulinemia, Obesity, Ovarian cancer, Smokers

Supplements: Fiber, Guar gum, Oat fiber, Pectin, Psyllium (Plantago psyllium)

Miscellaneous: HDL-cholesterol, Insulin, LDL-cholesterol, Triglycerides

Uric Acid in Fructose-Induced Metabolic Syndrome.

Posted on December 7, 2006 by Dr. Gary Pack

The metabolic syndrome is the cause of a worldwide epidemic consisting of: Obesity, poor tolerance to glucose, hyperinsulinemia, hyperuricemia (high serum uric acid,) hypertriglyceridemia, and hypertension, which are all risk factors for cardiovascular disease. The metabolic syndrome is seen in 27% of the population of the United States and the diagnosis of metabolic syndrome triples […]

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