Phosphatidylserine (PS) is a complex fatty chemical believed to be important in the functioning of the human brain. This study was a review of the medical literature done on the subject. In all, 127 articles were reviewed regarding PS, cognitive activity, cognitive aging, and retention of normal cognition.
PS is necessary for normal nerves and healthy myelin*. Aging of the human brain is accompanied by biochemical changes and reduced electrical transmission of nerves. Importantly, PS therapy improves memory recall and the formation of new memories. PS at 300-800 mg/d slows brain deterioration and reverses structural and biochemical abnormalities. It is well-absorbed, crosses the blood/brain barrier, improves mental focus, improves language skills, and can even improve reflexes.
CONCLUSION: PS appears to be especially useful in the aging process with problems associated with cognitive dysfunction, possibly due to myelin destruction. Therapy with PS has been found to be useful in these cases.
NOTE: *Myelin is the fatty layer that surrounds parts of nerve cells and increases the speed of nerve cell electrical activity. It is found in the white matter of the brain and in peripheral nerves. Myelin acts to maintain the electrical charge in nervous tissues.
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