Camu-camu (Myrciaria dubia), a fruit from Peru, contains vitamin C and anthocyanins, antioxidants. The seeds have not been well-studied, but their main ingredient is betulinic acid. Anti-inflammatory activity was found in those seed extracts.
Paw swelling (edema) was induced in mice by an inflammatory agent to test camu-camu. One control group was treated with distilled water, another was pretreated with a camu-camu seed extract, and a third was treated by an anti-inflammatory hormone (dexamethasone). The paw edema was “perfectly” prevented by dexamethasone. Pretreatment with camu-camu extract “significantly” reduced the paw edema.
The cellular production of nitric oxide (NO) with camu-camu treatment was studied in cells. NO production was inhibited by camu-camu extract. The active ingredient was found to be betulinic acid, a triterpene chemical. The fruit pulp of camu-camu has not been found to be anti-inflammatory and does not contain betulinic acid. (The fruit pulp does contain ellagic acid.)
CONCLUSION: The seeds of camu-camu should be a good food material with anti-inflammatory effects. “Camu-camu seed may be an important source of health food.”
To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon.