Bromelain is a protein-digesting enzyme from the fruit and stem of pineapple (Ananas comosus). The usual commercial source is the stem. Bromelain works in a wide range of pH from 5.5 to 8.0 and is well absorbed in the digestive tract. Activities of bromelain include fiber-dissolving, anti-edema, anti-clot and anti-inflammatory properties (with very low toxicity).
In mice the protein-digesting activity of bromelain in the digestive tract is increased by sodium bicarbonate. There is evidence for the benefit of bromelain in cancer treatment through a variety of different cellular mechanisms.
Bromelain can minimize or prevent the severity of heart pain (angina pectoris) and transient ischemic attacks (of the brain). It treats inflammation and clotting of the veins, and is believed to dissolve cholesterol plaques. It works well for most cardiovascular diseases (CVD) and has been shown to reduce the CVD risk factors.
Bromelain counteracts the diarrhea caused by certain bacteria, such as Vibrio cholera and Escherichia coli. Used before surgery, bromelain shortens the duration of post-surgical pain and inflammation. As well, it is used to treat sports injuries.
Due to its content of escharase enzyme, bromelain cream is good for removing the tissues following a severe burn. Dead tissue is removed without harming the unburned skin.
CONCLUSION: Bromelain has a number of beneficial effects on the body in diseases such as cancer, diabetes, cardiovascular diseases, and injury with low toxicity.